- Title: Lab-grown bones successfully transplanted, says Israeli firms
- Date: 8th December 2016
- Summary: HAIFA, ISRAEL (DECEMBER 4, 2016) (REUTERS) LIQUID BEING INJECTED ONTO SHEEP BONES DRIPPING LIQUID ON BONES VARIOUS OF TEST TUBE DRAWING LIQUID LABORATORY ASSISTANT LABORATORY ASSISTANT DRAWING LIQUID FROM TEST TUBE EMPLOYEES AT BONUS BIOGROUP WALKING INTO OFFICE SIGN READING 'BONUS BIOGROUP' ORA BURGER, VICE PRESIDENT OF REGULATION AFFAIRS AT BONUS BIOGROUP AND ATARA NOVAK, HEAD OF RESEARCH AT BONUS BIOGROUP WALKING INTO OFFICE BURGER AT DESK (SOUNDBITE) (English) ORA BURGER, VICE PRESIDENT OF REGULATION AFFAIRS AT BONUS BIOGROUP, SAYING: "What we are announcing to the world is that real success in our clinical study in regenerating new bone, regenerating bone in maxillofacial site in the jaws, it was 100 percent successful in all 11 patients, and all 11 patients got their dental implants." BURGER (SOUNDBITE) (English) ORA BURGER, VICE PRESIDENT OF REGULATION AFFAIRS AT BONUS BIOGROUP, SAYING: "Our previous clinical study was in the maxillofacial bone, and now we are going to conduct a clinical study in the extremities, long bones. In order to do this we have done preclinical studies in animals, in sheep." BURGER (SOUNDBITE) (English) ORA BURGER, VICE PRESIDENT OF REGULATION AFFAIRS AT BONUS BIOGROUP, SAYING: "After a few weeks and a few months, the patient has full, rigid dense bone of his own. What we inject is a live bone. This is the first time ever that it's been done." LABORATORY RESEARCHERS WORKING IN CLEAN ROOM ATARA NOVAK, HEAD OF RESEARCH AT BONUS BIOGROUP AT DESK (SOUNDBITE) (English) ATARA NOVAK, HEAD OF RESEARCH AT BONUS BIOGROUP, SAYING: "We inject our semi-solid product inside of this defect and here we can see 12 weeks later that the bone is functional, we can see a full bone, a whole bone which is strong and hard and functional." SHEEP BONE WITH DEFECT AND SHEEP BONE AFTER 12 WEEKS VARIOUS OF LAB ASSISTANTS AT WORK IN CLEAN ROOM
- Embargoed: 23rd December 2016 11:35
- Keywords: Israel bones transplant stem cells biotech
- Location: HAIFA, ISRAEL
- City: HAIFA, ISRAEL
- Country: Israel
- Reuters ID: LVA0015C0TLXX
- Aspect Ratio: 16:9
- Story Text: Israeli biotech company Bonus Biogroup's lab-grown, semi-liquid bone graft was successfully injected into the jaws of 11 people to repair bone loss in an early stage clinical trial.
The material, grown in a lab from each patient's own fat cells, was injected into and filled the voids of the problematic bones.
Over a few months it hardened and merged with the existing bone to complete the jaw, it said.
The announcement was made in a statement to the Tel Aviv Stock Exchange and Bonus Biogroup presented its results at the International Conference on Oral and Maxillofacial Surgery in Spain on Monday (December 5).
The company, which has raised $14 million, said it plans to dual list on Nasdaq in the coming months.
"For the first time worldwide, reconstruction of deficient or damaged bone tissue is achievable by growing viable human bone graft in a laboratory, and transplanting it back to the patient in a minimally invasive surgery via injection," said Chief Executive Shai Meretzki.
Meretzki previously founded Pluristem Therapeutics which works with stem cells and is one of the more advanced Israeli biomed companies.
Ora Burger, vice president of regulation affairs at Bonus Biogroup, told Reuters that a clinical study will be carried out 'in the extremities, long bones'.
- Copyright Holder: REUTERS
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